Senior Director, Pharmacokinetics, Dynamics, Metabolism and Bioanalysis, Protein Therapeutics
Core
Lead scientific and operational oversight for PK/PD and bioanalytical activities for protein therapeutic drug candidates from discovery through FIH trials.
Role type
Senior Director, Protein Therapeutics PK/PD & Bioanalysis
Builds
Protein therapeutic drug candidates (bispecific antibodies, ADCs, fusion proteins) for immunology and oncology
Domain
Biopharmaceuticals / Protein Therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Protein therapeutic discovery leadership, ADME concepts, FcRn biology, TMDD, Immunogenicity, Ligand binding assay design, Mass spectrometry, Translational PK/PD modeling, Human dose prediction, Cross-functional team management
Preferred skills
PBPK modeling, Immunology/Oncology program support, Hybrid-LC/MS assay troubleshooting, Research-driven pharma experience
Technologies
Phoenix WinNonlin, Berkeley Madonna, MATLAB
Responsibilities
Oversee design and interpretation of PK, immunogenicity, and ADME studies; Mentor and manage a multi-tiered team of scientists; Design and analyze in vitro and in vivo studies for drug disposition and pharmacological response; Contribute to global PDMB strategy across Boston, South San Francisco, and West Point locations
Seniority
Senior Director, strategic leadership with hands-on scientific oversight
