Senior Principal Scientist I - Functional Biomarkers
Core
Lead a group of scientists to develop, validate, and implement complex immunophenotyping panels and functional biomarker assays in a regulated environment.
Role type
Senior Principal Scientist (Functional Biomarkers)
Builds
Complex cell staining panels and functional biomarker assays for clinical programs
Domain
Biopharma / Immunology / Flow Cytometry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Flow cytometry instrumentation and troubleshooting, high-parameter panel development, cell sorting, assay design, method validation, analytical interpretation, people management, regulatory compliance (GLP/GCLP), AI tools for data analysis
Preferred skills
Immunology expertise, complex immunophenotyping assay development in clinical trials, laboratory information systems (LIMS), electronic laboratory notebooks, biological sample collection, software/equipment validation, mass spectrometry, Quality Assurance experience, regulatory filings, clinical trial operations
Technologies
Flow cytometers, Watson LIMS, AI tools
Responsibilities
Lead and manage local teams to develop and validate complex cell staining panels exceeding 30 colors, oversee method development and transfer at CROs, serve as flow cytometry subject matter expert for data interpretation, lead global project teams to operationalize testing strategies, prepare SOPs and study plans, implement AI tools to streamline workflows, ensure regulatory and safety compliance
Seniority
Principal, hands-on IC with team leadership
