Senior Scientist
Core
Lead and support daily operations in the Scale-up Lab for upstream and downstream biologics processes, including bioreactor fill/harvest, chromatography, and filtration.
Role type
Senior Scientist (Biologics Process Development)
Builds
Biologics assets for clinical and commercial manufacturing
Domain
Biopharmaceuticals / Biologics Manufacturing
Required skills
Upstream Processing (Mammalian Cell Culture), Downstream Processing (Harvest, Chromatography, Filtration), cGMP knowledge, Bioreactor operations, Chromatographic skid operation, Filtration skid operation, Buffer preparation, Process tech transfer, Process investigations, Single-use manufacturing, Automation
Preferred skills
Pilot Plant experience, Manufacturing experience, Statistics, Design of experiment, Data analysis
Technologies
Bioreactors, Chromatographic skids, Filtration skids
Responsibilities
Lead/support daily operations in the Scale-up Lab including bioreactor fill/harvest, inoculation, sampling, feeding, operating chromatographic and filtration skids, buffer preparation, run monitoring/troubleshooting; Prepare/review technical documents including campaign summary reports and batch records; Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing; Introduce, evaluate, and implement innovative new process technologies and capabilities; Identify and implement process transfer improvement initiatives with internal stakeholders; Support GMP-related activities for BD External Manufacturing programs (as needed); Maintain a safe work environment in the Scale-up lab
Seniority
Senior, hands-on IC
