Scientist, Non-Viral Gene Editing Platforms
Core
Develop next-generation engineered cell-based therapies (CAR-T) using non-viral gene editing platforms to treat hematologic malignancies, solid cancers, and autoimmune diseases.
Role type
Senior IC scientist (cell therapy/gene editing)
Builds
Engineered CAR-T cells and non-viral gene delivery platforms (e.g., lipid nanoparticles)
Domain
Biotechnology / Cell Therapy / Gene Editing
Required skills
Non-viral gene editing, CAR-T cell generation, flow cytometry, molecular biology, DNA design tools, aseptic technique, T cell culture, data analysis
Preferred skills
CRISPR/Prime editing, in vivo non-viral gene delivery, multi-color flow cytometry, complex panel design, ELN documentation
Technologies
Benchling, Geneious, Incucyte, FlowJo
Responsibilities
Execute experiments and record ELN entries; optimize base ex vivo editing platform; generate and characterize engineered CAR-T cells; troubleshoot routine problems; present findings in multidisciplinary meetings
Seniority
Senior, hands-on IC