Senior Scientist, Gene Delivery and Editing Process Development
Core
Design, execute, and optimize upstream development experiments and production processes for next-generation viral vectors (LVV and AAV) to support cell therapy clinical programs.
Role type
Senior Scientist, Process Development (Upstream)
Builds
Viral vector production platforms and clinical-grade cell therapies
Domain
Biopharmaceuticals / Gene Therapy / Upstream Process Development
Required skills
suspension culture of mammalian cells, viral vector process development, DoE design and execution, stirred tank bioreactor scale-up, cross-functional collaboration, technical writing, lab maintenance
Preferred skills
upstream process intensification (fed batch, perfusion), process-analytical technology (PAT), cell line development, media and feed optimization, process modeling, metabolic flux analysis
Technologies
shake flasks, stirred tank bioreactors, DoE tools, CDMO/CRO platforms
Responsibilities
Design and troubleshoot upstream experiments, optimize production processes for scale-up, lead platform development strategy, coordinate work of junior colleagues, support tech transfer and external collaborations, maintain laboratory notebooks and technical reports
Seniority
Senior, hands-on IC with leadership responsibilities