Scientist, High-Throughput Protein Expression and Purification
Core
Execute and advance scalable high-throughput protein expression, purification, normalization, and characterization workflows for antibody and biologics discovery programs.
Role type
Senior hands-on IC scientist (high-throughput protein production)
Builds
Fit-for-purpose protein reagents and therapeutic molecules for discovery programs
Domain
Biopharmaceuticals / Protein Sciences / Laboratory Automation
Required skills
mammalian protein expression, protein purification, chromatography, cloning, experimental design, data analysis, troubleshooting, SOP development
Preferred skills
laboratory automation, liquid handlers, robotic workstations, workflow scripting, Python/R, ELN/LIMS, next-generation sequencing, display-based screening
Technologies
HEK293, CHO, SEC, HPLC, SDS-PAGE, Octet, liquid handlers, robotic workstations, automated purification systems
Responsibilities
Execute high-throughput protein production workflows; Design and optimize transient mammalian expression workflows; Perform automated protein purification and quality assessment; Operate and maintain liquid handlers and robotic workstations; Develop robust and scalable workflows; Plan and execute experiments and analyze data; Partner with cross-functional teams to coordinate production requirements; Evaluate and implement emerging technologies and automation solutions; Establish and maintain best practices and SOPs; Lead root-cause analysis and continuous-improvement initiatives
Seniority
Senior, hands-on IC
