Senior Scientist, Translational Development
Core
Lead preclinical laboratory studies and mechanism of action research for late-stage immune-oncology programs to support clinical development and regulatory strategies.
Role type
Senior Scientist, Translational Development (Immuno-Oncology)
Builds
Preclinical data packages for late-stage (Phase 2+) immuno-oncology assets
Domain
Biopharma / Immuno-Oncology / Translational Medicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Multi-parameter flow cytometry, cell sorting, cellular immune effector assays (ADCC, ADCP, T-cell killing), cytokine analysis (ELISA/MSD), bulk/sc-RNA-seq, syngeneic and CDX-based efficacy studies, tumor immunophenotyping, transcriptomic profiling, spatial technology platforms
Preferred skills
Experience with spatial technology platforms (Akoya, Visium, COSMX)
Technologies
Akoya, Visium, COSMX, ELISA, MSD, sc-RNA-seq
Responsibilities
Perform preclinical/laboratory studies for late-stage BMS assets; deliver data supporting translational strategies including biomarkers, patient selection, dose/schedule, and resistance mechanisms; interface with research scientists to ensure information flow; maintain written reports and present results; contribute to external preclinical collaborations
Seniority
Senior, hands-on IC
