Senior Scientist, Cell Therapy TRC In Vivo Pharmacology
Core
Lead functional workstreams for engineered immune cell therapy programs from target concept to IND filing, designing and executing complex in vivo pharmacology studies in murine tumor models.
Role type
Senior Scientist, In Vivo Pharmacology (Cell Therapy)
Builds
Next-generation engineered immune effector cell therapeutics for cancer and chronic diseases
Domain
Biopharma / Immuno-oncology / Cell Therapy
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
in vivo immuno-oncology modeling, murine tumor model development (syngeneic, xenograft, T-cell driven), experimental design and execution, scientific authorship, regulatory and IP filing support, cross-functional scientific leadership
Preferred skills
gene editing technologies (CRISPR, AAV, non-viral delivery), mechanistic understanding of immune effector cell biology, influence project direction in matrixed teams
Technologies
CRISPR, adeno-associated viral vectors, non-viral delivery
Responsibilities
Lead functional workstreams on cell therapy research projects from target concept to IND; Design, execute, and interpret complex in vivo pharmacology studies; Author high-quality scientific documents, presentations, and regulatory filings; Supervise and mentor research associates; Present complex concepts to governance and departmental audiences
Seniority
Senior, hands-on IC with mentorship responsibilities