Senior Scientist, Inflammation Biomarkers & Translational Research
Core
Lead end-to-end biomarker strategy and translational research for clinical programs targeting inflammatory and fibrotic diseases, integrating multi-omic and clinical datasets to inform drug development and regulatory decisions.
Role type
Senior Scientist, Biomarker & Translational Science
Builds
Clinical biomarker strategies, assay qualifications, and translational study designs for Phase I-III and registrational studies
Domain
Biopharmaceuticals, Immunology, Inflammation Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Human immunology, Inflammation biology, Biomarker strategy design, Assay validation, Regulatory science, Multi-omic data integration, Clinical trial design, Scientific publication, Patent development, Vendor management
Preferred skills
Phase I-III trial leadership, Health authority interaction, High dimensional platforms (flow/mass cytometry, single-cell, spatial), Data analysis tools (R, Python)
Technologies
R, Python, Flow cytometry, Mass cytometry, Single-cell sequencing, Spatial imaging, Digital pathology
Responsibilities
Lead end-to-end biomarker strategy from early research through registrational studies; Define and implement pharmacodynamic, prognostic, and predictive biomarkers; Design and oversee human-relevant translational studies using primary human samples; Integrate multi-omic, spatial, imaging, and clinical datasets; Author and review clinical biomarker sections for protocols and regulatory documents; Present data at conferences and author scientific publications; Engage with health authorities and external collaborators; Mentor junior scientists and shape portfolio-level strategy
Seniority
Senior, hands-on IC with strategic leadership
