Senior Scientist II, Precision Medicine Translational Research Immunology
Core
Lead clinical biomarker discovery by profiling clinical samples using single-cell and spatial omics to understand drug mechanism of action and drive patient selection strategies for inflammatory and autoimmune diseases.
Role type
Senior Scientist II, Precision Medicine Translational Research Immunology
Builds
Clinical biomarker hypotheses and data-informed patient selection strategies for drug development programs.
Domain
Immunology, Immuno-oncology, Single-cell genomics, Spatial omics
Deliverable
production ML models | dashboards & analysis
Required skills
Single-cell RNA-Seq, CITE-Seq, Spatial transcriptomics/proteomics, Molecular pathology (IHC, ISH), Image analysis (Visiopharm, HALO), Bioinformatics (R, Python), Cloud/HPC environments, Machine learning frameworks
Preferred skills
None explicitly stated as preferred
Technologies
CosMx, Xenium, Visium, AWS, R, Python, Visiopharm, HALO
Responsibilities
Lead design, execution, and analysis of complex genomic profiling experiments; Perform image analysis for spatial transcriptomics and proteomics; Design computational pipelines for spatial omics data; Optimize assay performance and ensure data quality; Survey and validate novel scientific methodologies.
Seniority
Senior, hands-on IC with leadership responsibilities
