Research Fellow, Infection Cell Biology and Expansion Microscopy [LKCMedicine]
Core
Lead independent research on the spatial organization of host and viral organelles during infection using expansion microscopy and super-resolution imaging to uncover mechanisms of membrane biology and connect them to therapeutic strategies.
Role type
Senior Research Fellow (Infection Cell Biology & Advanced Microscopy)
Builds
Quantitative imaging capabilities for host-pathogen membrane interactions and independent research lines in infection biology.
Domain
Biomedical research, Infection biology, Cell biology, Structural biology
Required skills
Advanced fluorescence microscopy, Expansion microscopy, Super-resolution imaging, Mammalian cell culture, Molecular biology, Protein biochemistry, Quantitative image analysis, Genetic and chemical perturbation, Scientific leadership, Grant writing, Student mentoring
Preferred skills
Protein production, Structural characterization (X-ray, SAXS, cryo-EM), Image-based screening, Infection models, Membrane biology
Technologies
Expansion microscopy, Confocal microscopy, Super-resolution imaging, Image analysis software, Genetic tools, Chemical biology tools
Responsibilities
Lead independent research projects on host-viral organelle organization; Develop and validate expansion microscopy workflows; Investigate protein S-acylation effects on membrane architecture; Perform quantitative image analysis; Conduct cell culture, molecular biology, and infection experiments; Interpret results and propose new experimental avenues; Prepare manuscripts and grant applications; Supervise and mentor students at various levels; Maintain rigorous experimental records and biosafety compliance.
Seniority
Senior, independent research leader with mentoring responsibilities