Senior Scientist, Allogeneic T-Cell Therapy Process Development
Core
Developing, optimizing, and scaling clinical manufacturing processes for allogeneic CAR-T and TCR-T cell therapies.
Role type
Senior Scientist, hands-on IC in cell therapy process development
Builds
High-quality allogeneic T-cell products for clinical manufacturing
Domain
Biopharmaceuticals / Cell Therapy / Oncology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Human primary cell culture (T cells), Upstream/downstream process development, Flow cytometry, Genome editing (manufacture-ready tools), DNA/RNA transfection, Design of Experiments (DOE), Data analysis, Troubleshooting
Preferred skills
Immunology, CRISPR/Cas9/base editing, Viral transduction, GMP, Advanced characterization (dPCR, ELISA, NGS)
Technologies
CRISPR/Cas9, base editing, dPCR, ELISA, NGS
Responsibilities
Design and execute process development studies for cell culture and gene editing; Lead studies with minimal supervision; Collaborate cross-functionally for tech transfer and clinical readiness; Mentor junior scientists; Author regulatory filings and scientific publications.
Seniority
Senior, hands-on IC
