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Senior Scientist, Bioinformatics / Computational Biology

US - Cambridge - MA💼 Full-time💰 $115,992–$115,992🗓 2026-07-14 → 2026-07-30

Core

Transform complex human and pathogen datasets into decision-driving insights for antigen design, patient stratification, and translational strategy in vaccine and immune therapy programs.

Role type

Senior Scientist, Bioinformatics / Computational Biology

Builds

Antigen selection strategies, patient stratification models, and reproducible multi-omics analysis pipelines.

Domain

Biopharmaceuticals / Genomics / AI in Healthcare

Deliverable

production ML models | dashboards & analysis

Required skills

Genomic data analysis (NGS, variant calling, assembly), Machine learning & statistical modeling, R and Python (Bioconductor, pandas, scikit-learn), HPC and cloud computing (AWS, SLURM), LLM-powered agentic workflows, Molecular biology fundamentals

Preferred skills

Comparative genomics and phylogenetics, Single-cell RNA-seq analysis, Deep learning frameworks (PyTorch, TensorFlow), Biological foundation models, Agentic AI workflows (RAG, multi-agent systems)

Technologies

STAR, BWA, Bowtie2, Salmon, GATK, DESeq2, Nextflow, Git/GitHub, AWS, GCP

Responsibilities

Design and implement robust analyses across genomics and multi-omics to answer program-critical questions; Apply machine learning to discover biomarkers and predict antigen immunogenicity; Build and maintain reproducible workflows using HPC schedulers and cloud platforms; Design and integrate LLM-powered agentic workflows for literature mining and pipeline orchestration; Generate translational insights through differential expression and pathway enrichment; Pilot new tools in bioinformatics and AI/ML to scale successful methods.

Seniority

Senior, hands-on IC

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