Biophysics Scientist
Core
Execute high-throughput binding affinity characterization and mechanism of action studies on biologics using Surface Plasmon Resonance (SPR) instruments to support drug discovery.
Role type
Biophysics Scientist (Drug Discovery)
Builds
Binding affinity data and mechanistic insights for biologics in Amgen's therapeutic pipeline.
Domain
Biotechnology / Biophysics / Drug Discovery
Deliverable
production ML models | product features
Required skills
Surface Plasmon Resonance (SPR) instrumentation, binding affinity characterization, cross-species selectivity analysis, mechanism of action study, data analysis, collaboration with computational teams
Preferred skills
Protein chemistry, cell biology, membrane protein generation and characterization, lab automation (Bravo, Hamilton), bridging experimentation with computational modeling and ML
Technologies
Surface Plasmon Resonance (SPR), Bravo, Hamilton
Responsibilities
Implement and execute high-throughput binding affinity characterization on biologics; determine cross-species selectivity; study mechanism of action related to binding interactions; generate and analyze scientific data; interface with Computational Sciences Group to develop ML/AI models
Seniority
Mid-Senior level Scientist
