Senior Scientist (Analytical, Bioscience Category)
Core
Design, execute, and validate analytical assays using LCMS techniques to study linker payloads and antibody drug conjugates (ADCs) for oncology drug discovery.
Role type
Senior Analytical Scientist (ADCs and small molecules)
Builds
Analytical methods and data for ADC stability and impurity profiling
Domain
Oncology / Bioanalytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LC-MS/MS, HPLC, assay development, QTOF/Orbitrap instrumentation, protein biochemistry, small molecule analysis, impurity profile identification, quantitative bioanalytical methods
Preferred skills
SEC-HPLC, HIC-HPLC, automated liquid handlers, R/Python programming, sample extraction from biological matrices, stability monitoring in presence of enzymes
Technologies
LCMS, QTOF, Orbitrap, HPLC, R, Python
Responsibilities
Design and validate assays for ADC stability; elucidate mechanistic insights for ADC projects; build and maintain MS & HPLC methods; perform routine QC analysis of small molecules and biologics; interpret data for predictive modelling; share external research with peers
Seniority
Senior, hands-on IC
