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Senior Director, Small Molecule Drug Discovery in Inflammation Discovery

US - California - South San Francisco💼 Full-time🗓 2026-07-29 → 2026-09-27

Core

Lead early discovery inflammation research for small molecule programs from target identification through preclinical assessment to IND and FIH.

Role type

Senior Director, Small Molecule Drug Discovery (Inflammation)

Builds

Small molecule therapeutics for inflammatory conditions

Domain

Biopharmaceuticals / Immunology / Inflammation

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Immunology discovery research, small molecule drug discovery, target identification, medicinal chemistry, structural biology, PKDM, translational safety, team leadership, strategic portfolio management, cross-functional collaboration, mentorship

Preferred skills

PhD/MD in relevant discipline, target and drug hunting experience, expertise in Rheumatology/Gastroenterology/Pulmonology/Dermatology/Neuroscience, track record in academia or biopharma, ability to recruit and develop top talent

Technologies

None explicitly listed

Responsibilities

Develop integrated discovery strategies connecting target biology and modality selection; provide scientific and organizational leadership for inflammation programs; oversee pipeline advancement through key decision points; represent the function in governance forums; identify and evaluate new therapeutic opportunities; lead matrixed teams across sites and functions; mentor scientists in program leadership; provide expert guidance to senior management on science and portfolio; maintain scientific presence through publications and thought leadership; partner with R&D on clinical strategy and regulatory submissions

Seniority

Senior Director, strategic leadership with hands-on scientific oversight

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