Scientist II, Protein Engineering
Core
Develop and characterize antibody fragments with defined binding properties for the purification of biologics using protein engineering and molecular biology.
Role type
Scientist II, protein engineering (R&D)
Builds
Next-generation antibody-based affinity ligands for biologics purification
Domain
Biotechnology / Protein Engineering / Antibody Discovery
Deliverable
production ML models | product features
Required skills
protein engineering, molecular cloning, protein expression in microbial systems, data analysis, statistical tools, immunological assays (ELISA), display technologies (phage/yeast)
Preferred skills
antibody fragment experience, SPR/BLI analysis, automated liquid handling, high-throughput workflows, FPLC purification
Technologies
phage display, yeast display, FPLC, SPR, BLI
Responsibilities
Design and execute protein-engineering experiments to improve affinity ligand performance; Screen and characterize antibody fragments using display technologies; Analyze and integrate large experimental datasets to guide iterative engineering cycles; Contribute to project planning and coordinate experimental activities; Collaborate with multidisciplinary R&D teams.
Seniority
Mid-level, hands-on IC
