Bioinformatics Research Scientist / Senior Bioinformatics Research Scientist - Northcott Lab in the Center of Excellence in Neuro-Oncology Sciences (CENOS)
Core
Computational analysis of multi-omic datasets (single-cell, spatial, liquid biopsy) from pediatric brain cancer patients to drive discovery and treatment development.
Role type
Senior IC bioinformatics research scientist (cancer genomics)
Builds
Production pipelines and analytical frameworks for high-throughput sequencing data
Domain
Pediatric oncology / Cancer genomics / Multi-omics
Deliverable
production ML models | dashboards & analysis
Required skills
R, Python, single-cell/nucleus RNA-seq analysis, spatial transcriptomics, ATAC-seq, ChIP-seq/CUT&RUN, DNA methylation analysis, whole-genome sequencing (short/long-read), data integration and harmonization, workflow management (Nextflow/Snakemake), version control (Git), statistical analysis, algorithm implementation
Preferred skills
High-Performance Computing (HPC) environment experience, machine learning, artificial intelligence, manuscript preparation
Technologies
Illumina, PacBio, Oxford Nanopore, R, Python, Nextflow, Snakemake, Git
Responsibilities
Design and develop data analysis pipelines; perform statistical analysis and data visualization; troubleshoot computational analyses; establish protocols and best practices; evaluate new methods and technologies; contribute to automation of analysis methods; participate in interdepartmental projects
Seniority
Senior, hands-on IC
