Research Technician (Osterman Group – Metabolism-driven immunity)
Core
Execute and optimize protein production pipelines, biochemical assays, and molecular biology experiments to study how metabolism shapes immunity in phage-bacteria conflict systems.
Role type
Research Technician (Structural Biology & Biochemistry)
Builds
Protein samples for structural and functional analysis
Domain
Life Sciences / Structural Biology / Biochemistry / Metabolism
Required skills
protein expression and purification, enzymatic assays, kinetic and functional characterization, protein biochemistry, structure-function relationships, lab organization and inventory management
Preferred skills
protein engineering, X-ray crystallography workflows, Cryo-EM sample preparation, reconstitution of enzymatic pathways in vitro
Technologies
X-ray crystallography, Cryo-EM, expression systems, purification strategies
Responsibilities
Execute and optimize protein production pipelines including expression system selection and purification strategy design; Support and develop biochemical and enzymatic assays including kinetic and functional characterization; Support molecular biology and microbiology experiments relevant to protein function and pathway reconstitution; Participate in lab organization and management including ordering, inventory, and maintenance of laboratory infrastructure; Contribute to collaborative projects and develop independent experimental sub-projects depending on experience
Seniority
Junior to Mid-level, hands-on IC