Senior Associate Scientist, Delivery Technology
Core
Execute experiments for ligand discovery, screening, and characterization to support the development of novel RNAi therapeutics.
Role type
Senior Associate Scientist (Ligand Discovery)
Builds
Novel RNAi therapeutics for rare and common diseases
Domain
Biopharmaceuticals / RNAi therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
ligand discovery, high-throughput screening, cell-based assays, Next-Generation Sequencing (NGS) workflows, library preparation, PCR, plasmid preparation, cloning, mammalian cell culture
Preferred skills
single B cell isolation, automated assay development
Technologies
NGS, flow cytometry, cell-based assay platforms
Responsibilities
Execute key experiments for ligand discovery, screening, and characterization; Perform high-throughput screening and selection using cell-based assays; Execute NGS workflows including library preparation from single cells; Perform standard molecular biology techniques including PCR, plasmid preparation, and cloning; Run and assist in the development of automated, high-throughput screening assays; Maintain detailed and accurate records of all experimental work and data in electronic lab notebooks; Assist in data analysis, interpretation, and the preparation of presentations for internal meetings.
