Senior Scientist, Clinical Biomarkers - Oncology
Core
Translate preclinical biomarker findings into clinically feasible strategies for oncology programs from pre-IND through Phase 1/2 trials.
Role type
Senior individual-contributor clinical biomarker scientist
Builds
Clinical biomarker strategies and assay implementations for oncology drug candidates
Domain
Biopharmaceuticals / Oncology / Clinical Biomarkers
Required skills
Preclinical oncology translational research, fit-for-purpose assay technologies, clinical spatial omics assay design, bioinformatics analysis, complex biomarker dataset interpretation, clinical decision support
Preferred skills
Clinical spatial omics downstream bioinformatics, AI tool utilization for data analysis
Technologies
spatial omics, multiplex immunoassays, NGS, IHC, flow cytometry, ctDNA/liquid biopsy, cell segmentation, spatial clustering
Responsibilities
Capture and assess feasibility of key biomarkers from preclinical studies for clinical translation; Develop or qualify fit-for-purpose clinical biomarker assays and vendors; Conduct hypothesis-driven analysis and presentation of clinical biomarker data; Establish collaborative relationships for exploratory biomarker analysis; Partner to embed biomarker strategy into protocol design; Track and interpret emerging biomarker literature
Seniority
Senior, hands-on IC