Senior Research Associate, Molecular Biology and Sequencing
Core
Operate next-generation sequencing instruments and execute high-throughput molecular cloning workflows to generate design-build-test-learn data for a biomolecule synthesis platform.
Role type
Senior Research Associate (Molecular Biology & Sequencing)
Builds
NGS libraries, variant constructs, and pooled libraries for enzyme engineering and therapeutic molecule design
Domain
Biotechnology / Molecular Biology / Sequencing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
NGS library preparation, Illumina MiSeq/NextSeq operation, Gibson/Golden Gate cloning, pooled library assembly, sample tracking, protocol optimization, data interpretation
Preferred skills
Enzyme product characterization, raw data analysis (Python/R), high-throughput assay automation, yeast surface display, ELN/LIMS proficiency
Technologies
Illumina MiSeq i100, NextSeq 2000, ELN, LIMS
Responsibilities
Perform NGS library preparation, QC, and end-to-end operation of Illumina MiSeq i100 and NextSeq 2000 platforms; Execute high-throughput molecular cloning workflows (Gibson, Golden Gate); Assemble, quantify, and quality-control large pooled variant libraries; Manage sample barcoding and data/metadata tracking in ELN/LIMS systems; Develop and optimize robust, scalable protocols; Process and interpret raw sequencer output to convert reads into actionable insights; Collaborate with cross-functional partners in enzyme science and chemical biology; Maintain rigorous experimental documentation and lab safety compliance
Seniority
Senior, hands-on IC
