Senior Research Associate- Diagnostic Assay Development
Core
Executing technical development, optimization, and rigorous testing of novel Laboratory Developed Tests (LDTs) using single-cell and spatial genomics technologies to translate assay capabilities into clinical applications.
Role type
Senior Research Associate (Diagnostic Assay Development)
Builds
Laboratory Developed Tests (LDTs) and clinical-grade diagnostic assays
Domain
Life Sciences / Molecular Diagnostics / Genomics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
NGS workflows, nucleic acid extraction, PCR/qPCR, NGS library preparation, assay troubleshooting, optimization of molecular biology protocols, handling challenging clinical samples (FFPE, primary tumor cells, low-input)
Preferred skills
CLIA/CAP/ISO 13485 quality system experience, 10x Genomics platforms (Chromium/Xenium), automated liquid handling, microscopy techniques
Technologies
Chromium, Xenium, NGS platforms, automated liquid handling systems
Responsibilities
Execute complex single-cell and spatial genomics assays (sample processing, library preparation, sequencing), troubleshoot and optimize assay workflows, perform feasibility studies on new reagents and instrumentation, execute formal experiments for analytical validation studies (accuracy, precision, limit of detection), support transfer of robust assay workflows to CLIA operations
Seniority
Senior, hands-on IC
