Senior Scientist, LNP Process and Development
Core
Develop and scale-up lipid nanoparticle (LNP) formulations for nucleic acid delivery, focusing on process optimization and manufacturing of modified DNA and cofactor mRNA systems.
Role type
Senior Scientist, LNP Process and Development
Builds
Scalable and robust nucleic acid delivery systems (LNPs encapsulating modified DNA and mRNA)
Domain
Biotechnology / Nucleic Acid Delivery / Process Engineering
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Process development, scale-up, manufacturing of nanoparticle systems, experimental design, data analysis, complex technical problem solving
Preferred skills
Nucleic acid formulation experience (mRNA, DNA), T mixing, formulation scale-up, characterization techniques (DLS, encapsulation assays)
Technologies
T mixing, DLS
Responsibilities
Support process development and optimization for LNP formulation and scale-up; Design and execute experiments to improve LNP performance and manufacturability; Collaborate on characterization and evaluation of LNP formulations; Assist with technology transfer and scale-up activities; Analyze experimental data and maintain documentation; Stay current with LNP technology advancements
Seniority
Senior, hands-on IC