Scientific Associate I (Assay Development and Biophysics)
Core
Perform biochemical and biophysical assays to validate protein–ligand interactions and support hit validation, mechanism-of-action studies, and chemical probe discovery for a global drug discovery initiative.
Role type
Senior IC biophysical scientist (assay development)
Builds
High-quality chemical tools, reagents, and datasets for the human proteome
Domain
Biophysics / Drug Discovery
Required skills
Surface Plasmon Resonance (SPR) assay development, recombinant protein purification, kinetic analysis, affinity measurements, data analysis
Preferred skills
Complementary biophysical techniques (DSF, MST, ITC, BLI, fluorescence polarisation, MS), hit validation support, structural biology workflows, electronic laboratory notebooks
Technologies
Cytiva Biacore 8K, DSF, MST, ITC, fluorescence polarisation, BLI, mass spectrometry
Responsibilities
Design and perform protein-ligand binding experiments, develop and optimise SPR assays, analyse experimental data, maintain electronic laboratory notebooks, train laboratory members, contribute to scientific manuscripts
Seniority
Mid-level, hands-on IC