CareerPlan

Senior Biophysicist - Advanced Drug Discovery

Johannesburg, GautengFull-time2026-10-30
Hybrid

Core

Design and execute biophysical experiments to characterize drug-target interactions and develop assays for high-throughput screening in advanced drug discovery.

Role type

Senior IC biophysicist (drug discovery)

Builds

Novel therapeutic agents and biophysical characterization data

Domain

Pharmaceutical R&D / Biophysics

Required skills

Surface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC), Differential Scanning Fluorimetry (DSF), protein expression, protein purification, data analysis software, statistical methods

Preferred skills

Medicinal chemistry collaboration, computational biology integration, patent applications, scientific publications

Responsibilities

Design and execute biophysical experiments for drug-target characterization, develop and validate biophysical assays for screening, analyze complex experimental data, collaborate with multidisciplinary teams, mentor junior scientists, stay abreast of biophysical advancements, contribute to intellectual property generation

Seniority

Senior, hands-on IC