Research Fellow, Infection Cell Biology and Expansion Microscopy [LKCMedicine]
Core
Lead independent research on the spatial organisation of host and viral organelles during infection using expansion microscopy and super-resolution imaging to uncover mechanisms of membrane biology and connect them to therapeutic strategies.
Role type
Senior IC research fellow (infection cell biology & expansion microscopy)
Builds
Quantitative imaging datasets, manuscripts, grant applications, and a robust expansion microscopy capability within the lab.
Domain
Infection biology, cell biology, structural biology, and advanced microscopy
Required skills
advanced fluorescence microscopy, expansion microscopy, mammalian cell culture, molecular biology, protein biochemistry, quantitative image analysis, scientific writing, grant writing, student mentoring
Preferred skills
protein production, structural characterization (X-ray crystallography, SAXS, cryo-EM), image-based screening, infection models, membrane biology
Technologies
expansion microscopy, confocal microscopy, super-resolution imaging, structured illumination, STED, single-molecule localization microscopy, image-analysis software
Responsibilities
Lead independent research on host-viral organelle spatial organization; develop and validate expansion microscopy workflows; investigate protein S-acylation effects on membrane architecture; perform quantitative image analysis; conduct cell culture, molecular biology, and infection experiments; supervise and mentor students; prepare manuscripts and grant applications; maintain experimental records and biosafety compliance
Seniority
Senior, hands-on IC with mentoring responsibilities