Senior Scientist, Translational Science
Core
Support outsourced bioanalytical and biomarker activities for clinical programs, focusing on pharmacokinetic, immunogenicity, and PD assays.
Role type
Senior Scientist, Translational Science
Builds
Bioanalytical methods and clinical data packages for immunology therapies
Domain
Biotechnology / Immunology / Clinical Development
Required skills
Bioanalytical assay development, Pharmacokinetic (PK) analysis, Immunogenicity assessment, Validation planning, Regulatory compliance, Data integrity review, CRO coordination, Sample analysis planning (via careerplan.io/jobs/5439907008-senior-scientist-translational-science-at-spyre-therapeutics)
Preferred skills
Experience with extended half-life antibodies, α4β7, TL1A, IL-23, IL-17A/F targets
Technologies
Bioanalytical platforms, CRO management systems
Responsibilities
Manage day-to-day execution of outsourced bioanalytical activities; Provide scientific input to design and validation of bioanalytical methods; Review assay protocols and data packages for quality; Coordinate with CROs and internal partners; Plan clinical sample analysis across studies; Resolve issues in assay development or analysis; Evaluate bioanalytical data trends and communicate results.
Seniority
Senior, hands-on IC