Senior Scientist, Immunoassay Development, Critical Reagents & Reference Materials
Core
Lead the development, qualification, characterization, and lifecycle management of critical reagents and reference materials for immunoassays supporting Vaxcyte's vaccine pipeline.
Role type
Senior Scientist, Immunoassay Development (Critical Reagents & Reference Materials) (via careerplan.io/jobs/5250143008-senior-scientist-immunoassay-development-critical-reagents-reference-materials-at-vaxcyte)
Builds
Critical reagents, reference standards, assay controls, and customized immunoassay materials for vaccine analytical methods.
Domain
Biopharmaceuticals / Vaccine Development / Immunoassay Technology
Required skills
Monoclonal antibody generation and characterization, Antibody reagent generation and screening, Immunoassay platform expertise (ELISA, MSD, electrochemiluminescence), Stability study planning and execution, Lot-to-lot comparability assessment, CRO/CDMO management, GMP-regulated environment experience
Preferred skills
Antibody engineering, Recombinant antibody production, Hybridoma generation, Conjugated vaccine experience, GMP release support
Technologies
ELISA, MSD, electrochemiluminescence, bead-based assays, multiplex assays
Responsibilities
Lead laboratory studies for monoclonal antibody generation, screening, and characterization; Develop characterization strategies for antibody reagents including specificity, affinity, and stability; Manage reference standard and assay control activities including qualification and bridging; Oversee outsourced activities with CROs and vendors; Provide hands-on support for immunoassay method development and troubleshooting.
Seniority
Senior, hands-on IC