Scientist
Core
Lead assay development and analytical method development for monoclonal antibody, multispecific antibody, and mRNA vaccine projects within a laboratory setting.
Role type
Senior Scientist (Analytical Chemistry/Biopharmaceuticals)
Builds
Analytical assays and methods for vaccine and antibody product quality
Domain
Biopharmaceuticals / Vaccine Development
Required skills
Monoclonal antibody assay development, mRNA vaccine characterization, Liquid chromatography (LC), Size-exclusion chromatography (SEC), Ion-exchange chromatography (IEC), Host cell protein (HCP) and DNA (HCD) analysis, Experimental design, Troubleshooting, Data analysis and reporting, Method validation, Laboratory equipment maintenance
Preferred skills
Multispecific antibody characterization, Lipid nanoparticle (LNP) quantification, Bioseparation technologies, Peer-reviewed publication experience
Technologies
Electrophoresis, Size-exclusion chromatography (SEC), Ion-exchange chromatography (IEC), Liquid chromatography (LC)
Responsibilities
Lead and propose objectives for assay development across multiple project teams. Develop key process residual host cell protein (HCP) and host cell DNA (HCD) assays. Investigate methods and products with issues using LC technologies. Establish new capabilities for characterizing multispecific assembly. Develop an mRNA/lipid nanoparticle (LNP) quantification method. Evaluate and recommend new bioseparation analytical technologies. Coordinate the deliverables of analysts in support of project teams. Contribute to one or more peer-reviewed scientific publications.
Seniority
Senior, hands-on IC