Associate Director, Biotherapeutic Production and Characterization
Core
Lead protein production, purification, and fit-for-purpose characterization for discovery and early development of complex biologics, including multispecific antibodies and membrane proteins.
Role type
Senior IC Associate Director (Biotherapeutic Production & Characterization)
Builds
Assay-ready protein reagents, high-quality characterization data, and scalable production workflows for novel protein modalities.
Domain
Biotechnology / Protein Science / Bioengineering
Required skills
Protein expression (mammalian, bacterial, cell-free), purification methods (affinity capture, SEC), analytical characterization (purity, aggregation, stability), construct design & optimization, CRO/vendor management, team leadership, resource planning, automation adoption.
Preferred skills
Experience with multispecific antibodies, site-specific labeling, AI/ML-enabled tools, advanced judgment for complex scientific problems.
Technologies
Mammalian expression systems, affinity chromatography, size-exclusion chromatography, automation platforms, AI/ML tools.
Responsibilities
Oversee end-to-end production workflows; drive innovation for difficult antigens; establish production and characterization standards; lead portfolio planning and resource allocation; manage external partner relationships; represent the function on cross-functional teams; lead and develop a high-performing scientific team.
Seniority
Senior, hands-on IC with leadership responsibilities