Scientist
Core
Lead development of cell culture processes for clinical vaccine or therapeutic candidates, including process technology transfer for clinical-grade material manufacture to enable clinical trials.
Role type
Senior IC cell culture scientist (biomanufacturing)
Builds
Clinical-grade and toxicological-grade cell culture materials for vaccine and therapeutic candidates
Domain
Biotechnology / Biomedical Informatics / Vaccine Development
Required skills
mammalian cell culture development, microbial cell culture development, bioreactor operation, cGMP process development, tangential flow filtration (TFF), regulatory submission support, SOP generation, laboratory equipment maintenance, project planning, data analysis
Preferred skills
scalable transient transfection methods, upstream process optimization, technology transfer expertise (via careerplan.io/jobs/5253479007-scientist-at-axle)
Responsibilities
Lead development of cell culture processes for clinical vaccine or therapeutic candidates, Serve as the SME for technology transfer deliverables and regulatory submissions, Establish production processes using advanced bioreactor systems, Drive innovation and adoption of new technologies like TFF-based transient transfection, Plan and execute experiments for toxicological-grade material generation and cGMP production, Maintain upstream project schedules and coordinate with downstream processing groups
Seniority
Senior, hands-on IC
