Scientist / Senior Scientist, Assay Development (Reagents)
Core
Build and sustain the reagent supply infrastructure for a single-molecule proteome sequencing platform, owning the full lifecycle from formulation to lot release.
Role type
Senior Scientist, Assay Development (Reagents)
Builds
Reagents (enzymes, oligos, beads, solvents) for ProSE single-molecule expansion and library preparation workflows
Domain
Life sciences / Proteomics / Single-molecule sequencing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Biochemical reagent development, Quality-by-design (QbD), Design of Experiments (DOE), Stability study design, QC method development, SOP creation, Root cause analysis, Statistical data analysis, Hands-on bench work, Chemically reactive compound handling
Preferred skills
Proteomics reagents, Protein modification chemistry, Peptide-oligonucleotide conjugates, Single-molecule assay components, Automation platform liquid handling (Hamilton, ThermoFisher, Agilent)
Technologies
HPLC, Fluorescence-based functional assays, Hamilton platforms, ThermoFisher platforms, Agilent platforms
Responsibilities
Lead reagent formulation, characterization, and optimization; Design and execute stability studies and DOE experiments; Develop and qualify QC test methods and lot release protocols; Establish and maintain SOPs for integrated workflows; Analyze experimental data to identify trends and troubleshoot deviations; Forecast and maintain end-to-end reagent inventory
Seniority
Senior, hands-on IC
