Senior Scientist 1, Neuroscience
Core
Lead target validation and mechanism-of-action (MOA) assay development for Parkinson's disease using cellular and biochemical models.
Role type
Senior Scientist I, Neuroscience (IC)
Builds
Novel therapeutic targets and disease-relevant mechanisms for Parkinson's disease
Domain
Biopharmaceuticals / Neuroscience / Cell Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Cell culture (primary neurons, glia), Biochemistry, Enzymology, Confocal microscopy, High-content imaging, Protein detection/quantification (ELISA, MSD), Enzyme kinetic assays, Experimental design, Data interpretation
Preferred skills
iPSC-derived cells, Complex co-culture model systems
Responsibilities
Lead and support target validation and MOA assay development; Execute in vitro experiments in cell lines, primary neurons, iPSC-derived neurons, and glia; Build and execute biochemical and cell-based assays; Collaborate with cellular biologists, pharmacologists, and medicinal chemists; Support training of junior research associates; Maintain comprehensive experiment records; Uphold laboratory safety protocols
Seniority
Senior, hands-on IC