CareerPlan

Senior Principal Machine Learning Scientist

United States - Washington – BothellFull-time2026-11-06 → 2026-11-10

Core

Develop and advance machine learning methods that learn from and reason across complex biomedical, clinical, molecular, and scientific data to create scientific foundations for drug discovery and development.

Role type

Senior Principal Machine Learning Scientist (Research & Methodology)

Builds

Reusable AI methods, benchmarks, model components, and workflows for Pfizer's R&D organization

Domain

Biopharmaceuticals / Computational Biology / AI for Drug Discovery

Deliverable

production ML models

Required skills

Foundation models, multimodal learning, graph learning, agentic AI, causal ML, uncertainty-aware AI, experimental design, statistical analysis, Python, PyTorch/JAX

Preferred skills

Biological sequence modeling, knowledge graphs, clinical AI, omics data, generative AI

Technologies

PyTorch, JAX, Python, Graph Neural Networks (GNNs)

Responsibilities

Develop and extend advanced AI methods for biomedical research; Design and execute rigorous, reproducible experiments; Set evaluation standards and benchmarks for model robustness and generalization; Translate models into scientific evidence with domain experts; Build shared reusable foundations for cross-therapeutic application; Mentor colleagues and raise AI fluency across R&D

Seniority

Principal, hands-on IC with strategic influence