Principal Scientist--Pharmacokinetics, Dynamics and Metabolism
Core
Lead enzymology studies and ADME risk assessments to guide small molecule discovery and development decisions at Pfizer.
Role type
Principal Scientist, Pharmacokinetics, Dynamics and Metabolism (ADME)
Builds
Evidence-based recommendations for project progression and risk mitigation in drug discovery
Domain
Pharmaceutical R&D, ADME Sciences
Required skills
Enzymology, drug metabolism principles, in vitro-to-in vivo translation, DDI risk assessment, experimental design, data interpretation, scientific communication, mentoring
Preferred skills
PBPK modeling, transporter science, biotransformation, long-term culture systems, AI tool implementation
Technologies
Microsoft Copilot
Responsibilities
Design and execute enzymology studies, integrate ADME data to identify liabilities, lead ADME risk assessments, mentor scientists, identify capability gaps and propose novel approaches
Seniority
Principal, hands-on IC with mentorship
