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Senior Scientist, Computational Biotherapeutics Engineering

United States - Massachusetts - Cambridge💼 Full-time💰 $93,600–$93,600🗓 2026-05-28 → 2026-07-31

Core

Scientist implementing AI/ML methods for protein modeling, representation learning, and generative model development to advance biotherapeutic discovery and engineering.

Role type

Senior Scientist, Computational Biotherapeutics Engineering

Builds

AI/ML-driven design strategies for clinical molecules and antibody developability

Domain

Biopharmaceuticals / Computational Biology / Machine Learning

Deliverable

production ML models

Required skills

AI/ML for protein representation and structure prediction, Python programming, modern scientific/ML libraries (PyTorch, NumPy, SciPy), large-scale biological dataset analysis, HPC/cloud computing workflows

Preferred skills

Protein language models (ESM), generative structure models (RFdiffusion, BoltzGen), equivariant neural networks, antibody developability modeling, structure-based molecular modeling software (Rosetta, Schrödinger)

Technologies

PyTorch, NumPy, SciPy, scikit-learn, Slurm, AWS, Google Cloud, Rosetta, Schrödinger, MOE, FoldX, AlphaFold

Responsibilities

Implement AI/ML workflows for computational protein design in HPC/cloud environments, collaborate on antibody developability engineering models, analyze large-scale sequence and structure datasets, serve as technical expert in deep learning for protein sequences, optimize computational developability platforms

Seniority

Senior, hands-on IC

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