Senior Principal Scientist
Core
Lead route scouting, synthetic design, and process development for small molecule API manufacturing to deliver scalable, robust chemistry for global production.
Role type
Senior Principal Scientist (Process Development)
Builds
Scalable chemical API processes and technology for Pfizer's global manufacturing network
Domain
Pharmaceutical manufacturing / Small molecule API process development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Synthetic organic chemistry, process development, retrosynthetic analysis, catalysis, green chemistry, physical organic chemistry, statistical experimental design, automated laboratory technologies, regulatory compliance (impurities), intellectual property/patents, team leadership, cross-functional collaboration
Preferred skills
Asymmetric synthesis, computational methodology, AI tools in process development, continuous processing, robotics, genotoxic impurity control, scientific publishing
Technologies
HTE, data-rich experimentation, AI tools, continuous processing, catalysis, automated laboratory technologies, robotics
Responsibilities
Drive route scouting and synthetic design for development programs; develop safe, efficient, robust processes including full-scale qualification; lead matrix teams to deliver portfolio breakthroughs; advance scientific strategy for 2nd Generation API process development; conduct novel research and present findings; mentor colleagues and coach scientists; ensure safe and efficient operation of PDC facilities
Seniority
Senior, hands-on IC with strategic leadership and mentorship
