Scientist I, Immunology
Core
Design, execute, and troubleshoot cell-based assays using human primary immune cells to characterize the mechanism of action of protein therapeutics for immune-mediated diseases.
Role type
Scientist I, Immunology (hands-on IC)
Builds
Protein-based therapeutics for immune-mediated diseases
Domain
Biopharmaceuticals / Immunology
Deliverable
production ML models
Required skills
T cell immunobiology, human primary immune-cell isolation and culture, high-parameter flow cytometry, quantitative immunoassays, molecular biology and biochemistry techniques, cell-based functional assay development
Preferred skills
Industry experience in biologics discovery, experience with additional human primary immune-cell populations, high-throughput screening, laboratory automation, in vivo models
Technologies
PBMCs, purified T cells, ELISA, AlphaLISA, Meso Scale Discovery (MSD), PCR/qPCR, Western blotting
Responsibilities
Design and execute in vitro experiments with human primary immune cells, develop and optimize T cell functional assays, apply high-parameter flow cytometry and immunoassays, analyze reproducible data to support project decisions, collaborate with cross-functional partners, maintain experimental records
Seniority
Individual Contributor, Scientist I