Associate Director, Pharmacology
Core
Shape and execute preclinical pharmacology strategy across development programs to advance assets efficiently and credibly.
Role type
Associate Director, Pharmacology (senior IC)
Builds
Preclinical evidence packages and decision-critical data for drug development programs
Domain
Biopharma / Preclinical Pharmacology / Immunology
Required skills
Preclinical pharmacology strategy, mechanism of action, in vivo proof of concept, dose-response, PK/PD, CRO management, first-principles scientific reasoning, translational judgment, biomarker strategy, regulatory positioning
Preferred skills
Immunology, animal models, AI-enabled scientific workflows, immune-mediated disease biology
Technologies
Modeling, data analytics, literature mining, AI-enabled tools
Responsibilities
Design and oversee pharmacology studies to characterize target biology and exposure-response relationships; Develop integrated pharmacology plans covering efficacy, selectivity, and therapeutic index; Partner with DMPK, Toxicology, and Regulatory teams to integrate pharmacology into development strategy; Manage CRO-executed studies including protocol review, vendor oversight, and data quality; Apply scientific reasoning to pressure-test hypotheses and design focused studies
Seniority
Senior, hands-on IC