Senior Scientist I - Cell Culture Process Development
Core
Develop and characterize highly-productive CHO cell culture processes for cGMP biotherapeutic manufacturing, leading R&D initiatives to reduce cost of goods (COGs) through process optimization and technology transfer.
Role type
Senior Scientist I, Cell Culture Process Development
Builds
cGMP biotherapeutics (therapeutic proteins)
Domain
Biopharmaceuticals / Cell Biology / Process Engineering
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
mammalian suspension cell culture, Design of Experiments (DOE), process scale-up/down, bioreactor operation, technical troubleshooting, data analysis, GMP compliance
Preferred skills
cell metabolic modeling, process modeling (mechanistic/ML), bioreactor perfusion, Process Analytical Technology (PAT), upstream process development
Technologies
AMBR, shake flasks, bioreactors
Responsibilities
Develop and characterize CHO cell culture processes; Lead scientific R&D to reduce COGs; Design and analyze experiments using DOE; Collaborate cross-functionally on process development; Author technical reports and protocols
Seniority
Senior, hands-on IC