Scientist 3, Discovery Oncology
Core
Design and execute hypothesis-driven experiments to yield mechanistic insights for novel therapeutic targets in oncology drug discovery.
Role type
Senior IC discovery scientist (oncology)
Builds
Novel therapeutics and drug discovery pipeline
Domain
Biopharma / Oncology
Deliverable
production ML models | product features | dashboards & analysis | research
Required skills
mammalian cell culture, CRISPR-Cas9 gene editing, cellular pharmacology, mechanistic assays, Western blotting, qRT-PCR, protein interaction assays
Preferred skills
cancer signaling pathways, transcription factor and chromatin biology, NGS experiments (ATAC-seq, ChIP-seq, RNA-seq), advanced cellular imaging
Technologies
CRISPR-Cas9, lentiviral/transposon delivery, ATAC-seq, ChIP-seq, RNA-seq, live-cell microscopy, high-content imaging, immunofluorescence, FISH
Responsibilities
Design, execute, and interpret hypothesis-driven experiments; propose new ideas and identify key experiments to validate therapeutic targets; collaborate with multidisciplinary teams including Drug Discovery and Translational Medicine; present and discuss data at lab and cross-functional meetings
Seniority
Senior, hands-on IC