Scientist 3
Core
Independent execution and optimization of lipid nanoparticle (LNP) synthesis and formulation for nucleic acid delivery in vitro and in vivo studies.
Role type
Senior IC formulation scientist (LNP)
Builds
Non-viral delivery platform (LNPs encapsulating nucleic acids)
Domain
Biopharma / Nucleic acid delivery
Required skills
LNP synthesis and optimization, Design of Experiments (DoE), LNP characterization (DLS, Zeta potential, Ribogreen), statistical data analysis, scale-up and stability studies
Preferred skills
Tangential Flow Filtration (TFF), bioconjugation chemistry, FDA-regulated environment experience
Technologies
JMP, Prism, MS Excel
Responsibilities
Execute and optimize LNP synthesis, lead DoE-based screening campaigns, collaborate cross-functionally with biology/analytics/chemistry teams, support downstream processing and stability studies, analyze and present experimental data, troubleshoot formulation challenges
Seniority
Senior, hands-on IC
