Senior or Principal Scientist of Human Genetics
Core
Drive human-genetics support for CRM discovery and portfolio projects using population-scale biobanks and clinical cohorts to generate decision-relevant evidence.
Role type
Senior or Principal Scientist (Human Genetics)
Builds
Genetically supported targets, indications, and robust genetics packages for portfolio milestones including Candidate Selection.
Domain
Biopharmaceuticals, Cardio-renal-metabolic (CRM) diseases, Statistical Genetics
Deliverable
production ML models
Required skills
GWAS, PheWAS, fine-mapping, colocalisation, Mendelian randomisation, rare-variant analysis, polygenic risk scores, time-to-event analysis, statistical computing, R, Python
Preferred skills
AI-assisted tools, automated workflows, mentoring scientists
Technologies
R, Python
Responsibilities
Identify and prioritize genetically supported targets and indications; integrate genetic evidence with molecular QTL, transcriptomic, proteomic, and single-cell data; translate findings into recommendations for therapeutic concept and biomarker decisions; lead cross-functional Human Genetics initiatives; set scientific quality standards and establish scalable methods and workflows.
Seniority
Senior or Principal, independent scientific authority and strategic leadership
