Postdoc (m/w/d)
Core
Designing and validating optical biosensors to measure conformational dynamics of G protein-coupled receptors (GPCRs) and characterizing their responses to ligand and mechanical signals.
Role type
Postdoctoral Researcher (Developmental Genetics and Cell Biology)
Builds
Optical biosensors and pharmacological datasets for GPCR research
Domain
Life Sciences / Molecular Biology / Biophysics
Required skills
Molecular biology techniques for fusion protein cloning, Pharmacological assays in living cells (microtiter plates ≥ 96-well), GPCR/G protein/GRK/arrestin research experience, Structural modeling of GPCR-ligand interactions
Preferred skills
Design and validation of new biosensors in living cells
Technologies
Optical biosensors, Microtiter plates (96-well), Structural modeling tools
Responsibilities
Design and cloning of optical biosensors, Validation of optical biosensors in living cells, Application of optical biosensors to characterize GPCR responses, Design and performance of pharmacological assays, Analysis and visualization of large pharmacological datasets, Structural modeling of GPCR-ligand interactions