Postdoctoral Researcher (m/f/d) – Neuro–Tumor Signaling in Pancreatic Cancer
Core
Investigate how neuronal activity regulates pancreatic ductal adenocarcinoma (PDAC) progression by dissecting the GRIN2D–VGCC–Ca²⁺–CaMK signaling axis.
Role type
Postdoctoral Researcher (Neuroscience/Cancer Biology)
Builds
Insights into neuron–cancer communication and tumor-promoting signaling mechanisms
Domain
Neuroscience, Cancer Biology, Translational Medicine
Deliverable
research
Required skills
Neuronal functional assays, Live-cell calcium imaging, Whole-cell patch-clamp electrophysiology, Multi-electrode array (MEA) recordings, Confocal and super-resolution microscopy, Neuron–cancer co-culture systems, Tissue-slice models, Pharmacological perturbation, Genetic perturbation
Preferred skills
Experience in PDAC, Cancer neuroscience, Tumor–neuron interactions, Previous postdoctoral experience
Technologies
GRIN2D, VGCC, CaMKII/ERK, CaMKIV/CREB1/EZH2 pathways
Responsibilities
Dissect the GRIN2D–VGCC–Ca²⁺–CaMK signaling axis; Perform functional analysis of neuronal and neuron–tumor signaling using advanced microscopy and co-culture systems; Apply pharmacological and genetic perturbation strategies to analyze NMDAR and VGCC function; Work at the interface of fundamental neuroscience, cancer biology, and translational medicine.