PhD candidate (f/m/d)
Core
Investigate the role of neutrophils in early therapy resistance in human melanoma using multi-omics profiling, computational modeling, and clinically aligned biomarker stratification.
Role type
PhD candidate (Research Scientist)
Builds
Actionable, patient-specific predictions and resistance-targeting interventions in melanoma therapy
Domain
Cancer immunology / Tumor biology / Precision medicine
Deliverable
production ML models | research
Required skills
Molecular and cellular biology techniques, Functional immune cell assays, Cell culture, Flow cytometry, Microscopy, Proteomics workflows, Data analysis and visualization
Preferred skills
Experience with neutrophils or myeloid cells, Bioinformatics, Biostatistics
Responsibilities
Experimental setup and execution of neutrophil functional profiling, Functional assays of neutrophils (migration, phagocytosis, ROS production), Optimization of neutrophil functional assays for primary human samples, Few-cell proteomics for molecular characterization of neutrophil subsets, Multicolor flow cytometry of PBMCs and immune cell populations, Live-cell imaging and advanced microscopy for dynamic immune cell behavior analysis, Planning and execution of stimulation and inhibition experiments to dissect signaling pathways, Data processing, analysis, interpretation, and visualization of experimental results
Seniority
PhD candidate (Junior Researcher)