PhD Candidate - Immunogenomics of Arthritic Joint Disease
Core
PhD candidate applying genomic technologies and analytical pipelines to analyze single-cell, long-read sequencing datasets from diseased arthritic joints to understand disease mechanisms and identify novel drug targets.
Role type
PhD Candidate (Immunogenomics)
Builds
Insights into disease mechanisms, treatment resistance, and novel drug targets for arthritis therapies.
Domain
Biomedical research / Immunogenomics / Arthritis
Deliverable
research
Required skills
Genomic technologies, analytical pipelines, single-cell genetics analysis, transcriptome analysis, clonotype analysis, isoform analysis, mutation analysis
Technologies
Single-cell sequencing, long-read sequencing
Responsibilities
Analyze single-cell, long-read sequencing datasets integrating transcriptome, clonotypes, isoforms and acquired mutations from diseased arthritic joints; Access large-scale single-cell genetics analyses of hundreds of patients; Feed insights into the pipeline for producing and pre-clinically testing novel arthritis therapies.
Seniority
PhD Candidate