Senior Vice President, Translational Science
Core
Lead translational science programs from late discovery through Phase 1/2 clinical trials, defining strategy and guiding go/no-go decisions for small molecule drug development.
Role type
Senior Vice President, Translational Science (Senior IC Drug Developer)
Builds
Small molecule therapeutics for kidney disease (ADPKD) and related areas
Domain
Biotechnology / Small Molecule Drug Development
Required skills
Translational strategy definition, IND enabling work, early clinical strategy, disease model expertise, biomarker strategy, regulatory strategy, team leadership, external partner management, scientific judgment on incomplete data
Preferred skills
Rare disease experience, genetic/chronic disease programs, imaging biomarker qualification, Phase 1/2 study design, protein folding correctors/potentiators experience, early-stage venture-backed company leadership
Technologies
Small molecule drug development tools, CRO management platforms
Responsibilities
Define and lead translational strategy from development candidate nomination through Phase 1/2; Serve as the company's translational science voice guiding go/no-go decisions; Partner with CDO and CMO on dose selection and endpoints; Contribute to regulatory strategy and represent science in pre-IND interactions; Lead and develop the translational science team; Communicate program strategy to investors, partners, and the Board
Seniority
Senior Vice President, Strategy & Mentorship