Research Lab Technician II - Data Analysis
Core
Support ongoing studies in immunogenomics, cancer genomics, and therapeutics by performing molecular/cellular experiments and analyzing high-throughput sequencing and drug screen data.
Role type
Research Lab Technician II (Data Analysis & Wet Lab)
Builds
Novel therapeutic targets for acute myeloid leukemia (AML) and new therapeutic strategies
Domain
Translational genomics and experimental therapeutics (Cancer/Hematology)
Deliverable
production ML models | dashboards & analysis
Required skills
Next-generation sequencing data processing, differential expression analysis, variant calling, pathway enrichment, clustering, high-throughput drug screen analysis, flow cytometry data analysis, statistical analysis, public 'omics' resource mining, pipeline maintenance, data storage management, figure/table preparation
Preferred skills
Mouse handling, in vivo studies, NGS sample preparation, high-throughput assays, R, Python, GraphPad Prism, cancer biology background
Technologies
RNA-seq, whole-exome/genome sequencing, ATAC-seq, ChIP-seq, single-cell sequencing, TCGA, BeatAML, GEO, DepMap, high-performance computing cluster
Responsibilities
Process and run quality control on next-generation sequencing data; Perform downstream analyses including differential expression and variant calling; Analyze data from high-throughput drug screens and flow cytometry; Mine public 'omics' resources; Maintain and update analysis pipelines; Organize and manage lab datasets and metadata; Run jobs on high-performance computing cluster; Prepare figures and summaries for lab meetings and manuscripts
Seniority
Mid-level, hands-on IC